Welcome to The Little Yellow Pill website.
My name is Gail Hopen – together with hundreds of partners – I am an independent distributor for Lifevantage’s Protandim products. All our nutrigenomic products are home delivered – either by subscription or a once of order only, no strings attached. You can order your products with a discount of up to 25% by clicking the Order Buttons.
The information provided on this website is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition. This information is not intended to diagnose, treat, cure or prevent any disease. Never disregard medical advice or delay in seeking it because of something you may see or hear in this presentation.
On this webpage you will find information about an innovative breakthrough product that can help you improve and maintain cellular health in a natural way.
The videos below are:
- ABC Investigative Report (5:41)
- The Oxidative Stress Theory of Aging (2:34)
- Product Review by Dr. David Perlmutter, neurologist and Prof. Dr. Joe McCord, biochemist (7:07)
- Commercial Advertisement Protandim Nrf2 (2:51)
- Nrf2 Testimonials from several MDs and other Healthcare Professionals (9:57)
Try Protandim Nrf2 Synergizer yourself and experience what it will do for your cellular health. After that, put it in your food budget.
If you have any questions regarding the product, the science or if you are interested in measuring and monitoring your biological age, please contact us.
ABC Investigative Report with John Quinones
Dr. Brian Dixon, Ph.D. Senior Vice-President Research & Development LifeVantage
Dr. David Perlmutter, neurologist and Dr. Joe McCord, Ph.D.
Product commercial advertisement
Nrf2 Testimonials from several MDs and other Healthcare Professionals who are working with Protandim on a daily basis
Protandim Nrf2 Synergizer – Product Characteristics

Give Your Cells a Fighting Chance
The discovery that started it all. One of the leading theories of aging is the oxidative stress theory. It is based on the fact that our cells are constantly bombarded by free radicals (we call the subsequent damage “oxidative stress”). Our bodies naturally produce antioxidants to fight oxidative stress, but our antioxidant production begins to decline in our early twenties. Protandim Nrf2 Synergizer was sculpted to activate the Nrf2 pathway, a pathway responsible for antioxidant production. With peer-reviewed studies conducted by the likes of Harvard, Ohio State, the American Journal of Physiology and many more, Protandim Nrf2 Synergizer has been shown to reduce oxidative stress by 40% in just 30 days.*
Benefits
- Helps the body detoxify genes, keeping the master blueprint of the cell’s function intact *
- Reduces oxidative stress by 40% in just 30 days *
- Significantly reduces cellular stress through Nrf2 activation *
- Produces enzymes capable of neutralizing more than 1,000,000 free radicals *
- Helps to regulate survival genes *
- Supports the body’s natural ability to repair and rejuvenate its own cells *

Protandim Unleashes Powerful
Antioxidant Enzymes to Protect Cells
Protandim Nrf2 Synergizer’s proprietary formula activates the Nrf2 protein, also known as a “master regulator” of the body’s healthy stress response. Nrf2 Synergizer stimulates this protein, resulting in the body producing its own powerful, protective antioxidant enzymes: superoxide dismutase, heme-oxygenase, glutathione peroxidase and catalase. *
These enzymes function as potent antioxidants capable of neutralizing more than one million free radicals or reactive oxygen species. It’s the synergy of ingredients in Protandim that are effective in activating the Nrf2 pathway. There are other benefits of Nrf2 activation beyond cellular protection. Protandim supports the body’s natural cellular repair and rejuvenation and detoxification processes, keeping the master blueprint of the cell’s function intact.
Protandim Nrf2 Synergizer is the only supplement proven in a clinical study to reduce oxidative stress by an average of 40% in 30 days. It has been shown to increase superoxide dismutase levels by 30%, and catalase by 54%. When individuals were supplemented with Protandim Nrf2 Synergizer for 30 days, the age-dependent increase in lipid peroxidation was reduced to the level of a 20-year-old. This supports the scientific premise that the body is not only capable of making its own antioxidant enzymes, but also that their production can be activated by Protandim Nrf2 Synergizer to reduce oxidative stress and support the healthy aging process. *
40% Reduction in Oxidative Stress in 30 Days*
Exclusive LifeVantage Patents for Protandim
Patent No. 7,241,461 – Awarded 10 July 2019
Patent 7,579,026 – Awarded 25 August 2009
Patent No. 7,923,045 – Awarded 12 April 2011
* All claims are in line with the FDA regulations. Click here to read more. These statements are filed with the FDA and have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
Prof. David Sinclair, Ph.D. – Professor of Genetics at Harvard Medical School
Antioxidants don’t work (xenohormosis)
How he sees his role as an educator
Nobody has to live longer. It’s a choice
Full disclosure: David doesn’t support us
If you want to to read more or order Prof. Sinclair’s latest book
Lifespan: Why We Age and Why We Don’t Have To
Visit Dr. David Sinclair’s website >>> click here
To watch the full Talks at Google presentation >>> click here
Protandim Nrf2 Synergizer – The plant ingredients

Tumeric Root
Turmeric has been used for 4,000 years in both Ayurvedic and Chinese medicine to support good health. Current studies show that turmeric helps fight cellular stress, maintain joint health, and aid digestion. Turmeric is known to contain natural phenols called curcuminoids. *

Bacopa
Bacopa has long been hailed for its ability to promote cognitive abilities. Bacopa has been important in Ayurvedic medicine for centuries, used chiefly to enhance clear thinking and memory function. Studies suggest it provides strong cellular defense. It is also used to promote concentration, alertness and focus. The bacopa ingredient in Protandim is high in bacosides, the major constituent of which is the botanical compound called saponins. *

Milk Thistle
Milk thistle has been used for 2,000 years as an herbal remedy to support liver, kidney and gallbladder function. Several scientific studies suggest that substances in milk thistle (especially a flavonoid called silymarin) support healthy detoxification. *

Green Tea
Green tea is made from unfermented leaves and reportedly contains the highest concentration of powerful antioxidants called polyphenols, particularly catechins, of which epigallocatechin gallate (EGCG) is the most abundant. Protandim’s green tea extract contains 98% polyphenols. Green tea has been traditionally used for many health benefits, including maintaining body temperature and blood sugar levels already in a normal range, promoting digestion, supporting healthy mental processes and cardiovascular health. *

Milk Thistle
Milk thistle has been used for 2,000 years as an herbal remedy to support liver, kidney and gallbladder function. Several scientific studies suggest that substances in milk thistle (especially a flavonoid called silymarin) support healthy detoxification. *
Nrf2 Activation – Selected scientific publications

Pall M, Levine S, Nrf2, a master regulator of detoxification and also antioxidant, anti- inflammatory and other cytoprotective mechanisms, is raised by health promoting factors, Acta Physiologica Sinica, February 25, 2015, 67(1): 1–18 DOI: 10.13294/j.aps.2015.0001
Other links
Full article >>> click here
PubMed Abstract >>> click here
Full article >>> click here
PubMed Abstract >>> click here
Do your own PubMed Research
Visit Drs. Erik Sanders’s website to learn more about Pathway Biology and the impact on cellular metabolism, damage, deterioration and dysfunction.
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